Abstract
Deficiencies of trace metals (copper and zinc) are generally considered not to be a clinical problem, because these trace metals are widely distributed in the foods.
Recently, however, not a few cases of deficiencies of these trace metals in man during intravenous hyperalimentation have been reported. Thus, it has become important to have knowledge of these trace metals in clinical practice. The author reviews basic biochemistry, mechanisms and symptoms of deficiencies of these trace metals.
