Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
TRANSCATHETER INTRA-ARTERIAL INJECTION OF COMBINATION DRUGS AS NEOADJUVANT CHEMOTHERAPY FOR ADVANCED UTERINE CERVICAL CANCER
Yoichiro FUJIWARA, Seiji FUJITA, Izumi KUSUKI, Hiroshi TSUCHIYA
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Keywords: uterine cervical cancer, neoadjuvant chemotherapy, intraarterial injection of combination drugs
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1994 Volume 48 Issue 10 Pages 864-869

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Abstract
Five patients of uterine cervical cancer (stage IIb) underwent intraarterial injection of combination drugs (CDDP 70-80mg, ADM or Epi-ADM 40-50mg, MMC 20mg, 5-FU 500mg) for two times before the operarion or the radiation therapy (as neoadjuvant chemotherapy).
Tumor size and cancer invasion were reduced, and also the value of abnormal tumor marker declined to normal level in all patients as a result.
These results suggest that intraarterial injection of the combination drugs as neoadjuvant chemotherapy may be able to make succeeding operation or radiation more curative and lead better prognosis.
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© Japanese Society of National Medical Services
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