Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) infection. among hospitalized patients with hematological diseases in Kyoto National Hospital during past five years was studied. The incidence of infection was significantly higher among patients with hematological diseases than those with non-hematological diseases in the same ward. There were 11 patients 5 with myeloma, 3 with acute leukemia and 3 with malignant lymphoma. Ten patients were older than 50 years and 8 were male.
MRSA was cultured mostly from sputa and throat exudates. Urine was the following source in frequency. MRSA positive patients tended to cluster during certain periods, which suggested nosocomial tranomission. No relation was found between MRSA infection and patients' leukocyte or granulocyte count. MIND, IPM/CS or VCM were used and MRSA was eradicated in 7 cases. Four patients died of complicated MRSA infections.