Abstract
The authers reviewed the clinical application of genetic markers as; 1) cancer diagnosis (early detection of cancer, differential diagnosis between benign and malignant lesions), 2) speculation of the prognosis of cancer patient and prediction of chemosensitibity, and 3) determination of high risk people for cancer. It is no doubt that genetic markers is highly useful and going to be available in routine examinations for cancer patients. However, since genetic examination sometimes creates ethical problems, medical doctors should take care of its application and obtain an informed consent.