Abstract
Intravesical instillation of Maalox, known to be effective in the protection of gastric mucous epithelia, was performed in 3 cases with intractable massive bladder hemorrhage, resulting in successful hemostasis Three patients, comprising two cases of radiation cystitis and one case of cyclophosphamide-induced hemorrhagic cystitis, were seriously anemic because of severe bladder hemorrhage that was resistant to any other hemostatic therapies. Fifty to one hundred ml of undiluted Maalox was instilled into the urinary bladder and left in place for 30-60min, and this technique was performed once or twice a day every day. Bleeding ceased within 1 to 10 days (average 6.8 days) after initiation of Maalox therapy without any notable side effects in all cases. Because this treatment controls bladder hemorrhage using a simple technique without side effects, we suggest that intravesical instillation of Maalox may be one of the beneficial treatment for serious and chronic hemorrhagic cystitis like these cases
