Abstract
Review was made on the transmisson-mode of HCV with some recent pertinent litratures.
Incidence of posttransfusion hepatitis drastically reduced after introduction of anti HCV screening to donating blood in 1989-1992. However, many problems concerning the transmission-mode of HCV remained unresolved. Attention has been drawn to contaminated syringe (widely used in the past), dialysis, i. o. drug-users, needlestick accidents, acupuncture, tattoo and especially intrafamilial transmission. In endemic areas where a large outbreak of NANB-hepatitis recorded in the past, high positive rate of anti-HCV was demonstrated in the general population, and available evidence strongly suggests that contaminated syringe played a dominant roll in spreading of HCV.
Further works are in progress to clarify the roll of sexual, and vertical transmission route of HCV.
