Abstract
29 cases of de novo acute leukemia which were treated for the first remission induction between Jan. of 1990 and Sep. of 1995 were analysed with regard to the response of therapy and prognosis. Complete remission (CR) was obtained in 22 of 29 patients (86.2%). CR rate was 18 of 21 AML cases (85.7%), 7 of 8 ALL cases (87.5%) and 10 of 13 patients aged over 65 years old (76.9%), 15 of 16 patient aged under 65 y. o. (93.7%), respectively. 5-year survival rate in total cases was 30.7%. 5-year disease free survival rate was 33.9% in all CR cases (32.4% in AML, 62.5% in ALL, 17.9% in patients over 65 y. o., 46.4% in patients under 65 y. o., and 49.5% of patients who achieved CR by the first induction course, 28.5% of patients who needed 2 or 3 induction courses for CR, respectively). Though the acute leukemia has become a curable disease, the result for aged patients seemed to be not satisfactory.
