Abstract
We report a case of B cell lymphoma associated with rectal cancer and acute renal failure due to tumor lysis syndrome. An 83-year-old woman was admitted to our hospital because of abdominal distension and hematochezia. Enlarged inguinal lymph nodes, intra-abdominal masses involving the subcutaneous tissue, and abundant ascites were present. She was diagnosed as having B cell lymphoma from the results of cytology, surface marker studies and DNA analysis of abnormal cells from the ascites. Colonoscopy also revealed adenocarcinoma with a villous adenoma in Ra region. lmmediately after the admission, she rapidly developed acute renal failure due to the tumor lysis syndrome. Her renal function was improved by hemodialysis and steroid pulse therapy. However, chemotherapy was ineffective and she died of multiple organ failure three months after admission. At autopsy, the lymphoma involved various organs, macroscopically looking like carcinornatous pleuritis and peritonitis. Histological examination showed non-Hodgkin's lymphoma of the diffuse large cell type and there was no metastasis from her rectal cancer.
