Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
A STUDY ON TREATMENT OF RETROPERITONEAL FIBROSIS
Hideyuki WAKASUGI, Shuuichi ARAO, Yasuo MATSUURA, Fumitaka SONODA, Toshiro FUKUDA
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Keywords: retroperitoneal fibrosis, human pancreatic cancer cells, rat pancreatic acinar cells, culture experiment, anti-cancer drug
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1998 Volume 52 Issue 2 Pages 82-86

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Abstract
Retroperitoneal fibrosis shown in a patient with advanced gastric cancer was markedly improved by chemotherapy (5'-DFUR+MMC). In addition, fibrosis that appeared when human pancreatic cancer cells and isolated pancreatic acinar cells of normal rats were cultured was reduced by administration of anti-cancer drugs (MMC and 5-FU, respectively). The above results suggest that anti-cancer drugs are useful for the treatment of retroperitoneal fibrosis even at low doses.
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© Japanese Society of National Medical Services
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