Abstract
A case of a 54-year-old woman with psoriasis vulgaris (PV) who developed primary biliary cirrhosis (PBC) is reported. Liver dysfunction was at first pointed out in 1982 and despite vari-ous medications such as Strong Neo Minophagen-C, Shosaikoto (TJ-9), the transaminase level has persisted slight elevation. She was referred to our hospital in 1989. PBC was diagnosed because of positive for anti-mitochondrial antibody and elevation of IgM, more elevation of serum alkaline phosphatase and gamma-glutmyl transpeptidase than transaminase. Liver biopsy demonstrated the finding of non-suppurative destructive cholangitis with prominent lymphoid cell aggregates in portal areas which were regarded as Scheuer's stage I. Although both PV and PBC are considered as autoimmune disease respectively, their association is extremely rare. To our knowledge, this is the third reported case in the literature.
