Abstract
A 35 years old male with a history of schizophrenia developed neuroleptic malignant syndrome (NLM) by use of sulpiride and failed to respond to dantrolene or bromcriptine. The patient stayed in ICU for 32 days and was given supportive care such as mechanical ventilation, use of sedatives and muscle relaxants, and strict management of body temperature. He responded to the therapy and was discharaged in a good condition after 323 days of hospitalization. He has been followed for 4 years to this date and doing well only with use of etizolam as an outpatient.
It may be suggested from this case that NLM can be successf my managed with conservative and supportive care until the inducting agents are metabolized and excreted from body if it failes to respond to initial medication therapy.
