Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
MRI FINDINGS OF ALZHEIMER'S DISEASE IN EARLY STAGE
Atsushi MURAMATSUMinoru YAMADAKenji SATOHiroko ITOMakoto KIMURAHirotaka SAKAIHideki YAMAZAKIHidemitsu SAITOTatsuo CHIBAHaruo SHIBUYANoriko KURIHARA
Author information
JOURNAL FREE ACCESS

1999 Volume 53 Issue 6 Pages 398-401

Details
Abstract
We investigated whether morphological features can be observed on magnetic resonance imaging (MRI) in early Alzheimer's disease (AD). We classified AD patients into two groups according to mildly (n=12) or moderately (n=12) impairment, and we compared MRI head scans of these patients with scans of normal controls (n=14) with respect to volume of the temporal horn of the lateral ventricles and volume of the hippocampus.
Mildly-impaired patients showed a significantly larger volume of the temporal horn of the lateral ventricles than normal controls, but there was no difference between these groups in volume of the hippocampus. Moderately-impaired patients showed a significantly smaller hippocampal volume than mildly-impaired patients, but there was no difference between them in the volume of the temporal horn of the lateral ventricles. Moderately-impaired patients showed a significantly larger temporal horn of the lateral ventricles and smaller hippocampal volume than normal controls. Thus, we suggest that measurements of the volume of the temporal horn of the lateral ventricles is a useful adjunct diagnostic tool in the routine diagnosis of early AD
Content from these authors
© Japanese Society of National Medical Services
Previous article Next article
feedback
Top