Abstract
Human atrial natriuretic peptide (hANP) and brain natriuretic peptide (BNP) are released from volume everload in patients with hemodialysis (HD). But there have been few reports on the difference between type I and type II dialyzer about pre and post plasma levels of hANP and BNP.
We determined plasma hANP levels, plasma BNP levels and body weight pre and post HD in 32 patients without heart failure and pulmonary dysfunction (mean age: 59.7 years, mean duration of HD: 69.0 months).
The following results were obtained:
1) The mean plasma hANP levels of post HD was markedly lower than those levels of pre HD.
2) A positive correlation was recognized between %ΔhANP and %Δbody weight, however there was no correlation between %ΔBNP and %Δbody weight.
3) There was a significant difference in decreased levels of BNP and %ΔBNP between type I dialyzer group and type II dialyzer group.
We supposed that the levels of plasma BNP should be measured at pre-HD than post-HD.
