HORMONE RESISTANCE AND HYPERSENSITIVITY: CLINICAL STUDY OF CORTISOL RESISTANCE AND HYPERSENSITIVITY AND INSULIN HYPERSENSITIVITY

Abstract

Hormone resistance and hypersensitivity are generally caused by abnormalities of hormone receptors. They are characterized by discrepancy between clinical manifestations and serum hormone values. In hormone resistance, clinical findings due to increased serum hormone are not recognized. On the other hand, in hormone hypersensitivity, clinical findings due to decreased serum hormone are not recognized. Patients with resistance and hypersensitivity to cortisol, aldosterone, LH, FSH, TSH, ACTH and insulin have been reported. We also reported patients with cortisol resistance, cortisol hypersensitivity and insulin hypersensitivity.