Abstract
A regional correlation between EEG fractions and cerebral blood flow (CBF) was investigated by pixel-based statistical analysis. Eight right-handed normal male volunteers were measured twice at the same mental condition, i. e., at rest with eyes closed in a quiet examination room. Regional CBF (rCBF) was measured by positron emission tomography with using H_2^<15>O slow-bolus injection. Brain rCBF images were then transformed into a standard brain configuration which is based on a sterotaxic brain. There were marked inter-subject variations in EEG fractions with negligible intra-subjects difference. Regional CBF differences were noted as relative reduction of rCBF in the second scan mainly in the right hemisphere. Significant correlations were found between rCBF and certain EEG fractions. In particular, regional asymmetry in rCBF (left>right) was found in the frontal and temporal cortices which correlated with fractions of EEG higher than 8 Hz. The occipital brain rCBF correlated positively with theta and negatively with alpha and beta-2. It was concluded that the EEG-PET correlation study may be useful for understanding of the human brain.
