Abstract
Integrative medicine integrating conventional medicine (modern western medicine, MWM) with CAM is considered as the ideal medicine in the 21st century. The MWM is based on science, however CAM is based on experience which need scientific evidence. In order to certify the evidence of the effects and safety on CAM, bridging from MWM to CAM by the scientific methodology -biomedical engineering- is necessary. By the approach of biomedical engineering using thermography, laser, EEC, pulse diagnosis, the effects of CAM such as acupuncture, massage, meditation etc. were studied.