Abstract
Endoscopic Submucosal Dissection (ESD) has been increasingly accepted as a minimally invasive treatment
for the patients with early gastrointestinal cancers. However, reliable ESD technique demands high
maneuverability, and the success of the operation is dependent on each operator's skill. We have developed
a novel laser endoscopic system for ESD to overcome such technique-related difficulties. Compared
to conventional ESD using electrosurgical knives, an ESD method using the CO2 laser offers the advantages
of less risk of perforation and the prevention of extensive thermal damage, because the CO2 laser
is strongly absorbed by water. Furthermore, due to the non-contact technique associated with the CO2
laser and adequate visualization of the treatment area, the laser system may provide every endoscopist
with more precise and safer treatment.