Abstract
The advent of radiofrequency ablation (RFA) has changed the treatment strategy of hepatocellular carcinoma (HCC) in Japan. Although RFA is usually applied for the treatment of small HCCs measuring 3cm or less, the indications of RFA have been expanded to larger tumors by combining hepatic arterial embolization. Some tips have been developed to prevent complications, leading to a better prognosis even in the long term. On the other hand, recently, therapeutic results of RFA in liver metastasis patients have been reported and the types of patients who can benefit from liver RFA have been beginning to be understood.