Abstract
Cushing syndrome is characterized by elevated levels of circulating corticosteroids. In the majority of cases, it is caused by hypersecretion of corticotropin by the pituitary gland (Cushing disease). Selective venous sinus sampling is considered to be the gold standard for confirming the origin of ACTH secretion in patients with Cushing syndrome. We explain the procedure for precise results in relation to venous anatomy of cavernous sinus in selective venous sampling.