2016 Volume 31 Issue 1 Pages 18-25
Rabbits are the smallest animal species available for experiments of vascular IVR with the same devices used in humans. The mindset in animal experiments is described in the general statement. It is important to keep in mind the respect for animals in experiments and this mindset enables reproducible experiments.
Breeds and characteristics of rabbits used for experiments, as well as basic issues in the management of rabbits, are described in this paper. Next, anatomical issues necessary for IVR in rabbits are demonstrated. Last, it is introduced how to construct a liver tumor model with the VX2 tumor.
The importance of basic research is recognized by many IVRists, but in fact engagement in basic research while pursuing busy daily clinical practice is a great obstacle for doctors with no experience in basic research. We would be happy if this paper would be of some help for such doctors.
We expect a large number of basic studies to be conducted in Japan in the near future that will be helpful to the development of the world's first minimally-invasive treatment.
