2023 Volume 38 Issue 1 Pages 2-7
NBCA (n-butyl-2-cyanoacrylate) is a cyanoacrylate-based liquid adhesive used for endovascular interventions and has a major role in managing vascular abnormalities, bleeding, and many vascular diseases. NBCA reacts with ionic solutions such as blood or normal saline, and starts polymerization immediately causing vascular embolization. NBCA is typically used in combination with lipiodol for intravascular embolization to provide radiopacity and achieve an appropriate polymerization time. The embolic effect is permanent and has a strong embolic effect that does not depend on coagulation parameters, but it requires proficiency in handling due to the risk of serious ischemic complications and adherence to the catheter if not used properly. This article introduces the basics of NBCA such as its characteristics, precautions / preparations for use, mixing ratio, tips for injection, indications, contraindications, and possible complications, for safe use of NBCA.
