Pathological studies on dentigerous cyst and primordial cyst.

Abstract

Clinicopathological and histopathological studies on 85 cases of dentigerous cyst and primordial cyst were made. The results were as followws:

Of the 85 cases, 52 cases were dentigerous cyst, 27 cases were primordial cyst and 6 cases were multiple cyst. 35 of the 52 cases of dentigerous cyst occurred in the maxilla, and half of them occurred in the maxillary anterior region. 20 of the 27 cases of primordial cyst occurred in the mandible. 3 cases of primordial cyst and 2 cases of multiple cyst showed postoperative recurrence.

Keratinization of the epithelial lining with various degrees was noted in 30.8 per cent of the dentigerous cyst and in all of the primordial cyst. 15.4 per cent of the dentigerous cyst, 37.0 per cent of the primordial cyst and 66.7 per cent of the multiple cysts contained satellite cyst in the fibrous connective tissue wall. Melanocytes and melanin pigments were found in the epithelial lining of 7.4 per cent of the primordial cyst and 16.7 per cent of the multiple cyst, however, they could not be found in any cases of the dentigerous cyst.

Ultrastructurally, the keratinizing epithelium of the cysts showed regular stratification which was usually seen in the keratinizing squamous epithelium. On the other hand, the non-keratinizing epithelium showed no regular stratification, and showed wide intercellualr space, numerous intracytoplasmic small vesicles and short microvilli.