The effect of experimental tooth separation on emotional behavior in mice

Abstract

In the present study, the effect of experimental separation of the lower incisors on emotional behavior was examined in mice at day 1, 2 and 7 after separation treatment. Emotional behaviors were swimming behavior, climbing behavior and immobility behavior based on the modified forced swim test. The experimental incisor separation increased climbing behavior and decreased immobility behavior on day 1 and 2 after treatment. It is reported that an incisor separation in the mouse increases the turnover of the central noradrenergic system. Thus, from these results, it is suggested that incisor separation in mice temporarily influences emotional functions.