An ultrastructural study of koilocyte in oral papilloma

Abstract

Koilocytes were studied in oral papilloma from a 59-year-old man with transmission electron microscopy. The koilocyte was represented by irregular nuclei with coarse chromatin clumping. The clear perinuclear zone was almost completely lacking of a cytoplasmic component or an aggregate of some vacuoles. However, an increase of tonofilaments in the outer zone of the cells was noted. No virus particle was detected in the nuclei of the cells within the observed area.