We reported a case of Weil's disease developed Jarisch-Herxheimer reactions after administration of antibiotics.

Abstract

Leptospirosis is zoonosis caused by pathogenic bacteria called Leptospires that belong to Spirochaetales. We reported a 74 year-old man who had a sense of malaise and his body color is yellow. He had a conjunctival suffusion and muscle pain which had characteristically the calves. His blood test indicated elevated serum bilirubin, kidney impairment, or thrombopenia. We diagnosed him with Leptospirosis and started antibiotics. After starting antibiotics his blood pressure lowered by Jarisch-Herxheimer reaction, but it was getting better within 24 hours. He was discharged without any sequelae.