Abstract
Periodontal disease is considered as a lifestyle-related disease; various studies have been conducted and have suggested that diet and many nutrients are associated with the disease. In this study was investigated the efficacy of dietary supplement“ collagen and zinc jelly” during the treatment period; the randomized placebo controlled trial was conducted with 34 periodontal participants. The subjects were divided into the “collagen and zinc jelly” group (supplement group) and the placebo group randomly. Probing pocket depth (PD) and bleeding on probing (BOP) were evaluated as periodontal clinical parameters at baseline, 4, 8 and 12 weeks for all the subjects. As for the subjects with probing pockets 4mm or deeper at baseline, the mean PD of supplement group was 3.36 ± 1.34mm at 8 week, and it had a significantly decreased level compared with placebo group (3.69 ± 1.44mm, p< 0.05). Furthermore, the average score of BOP points in the supplement group was 7.79 points at 8 weeks, and 7.35 points at 12 weeks, they were significantly smaller than the placebo group (19.54 and 20.77, respectively, p<0.01)．These findings suggest a possibility that use of“ collagen and zinc jelly” supplement may prevent progression of periodontal disease.
