Journal of Advanced Computational Intelligence and Intelligent Informatics
Online ISSN : 1883-8014
Print ISSN : 1343-0130
ISSN-L : 1883-8014
Regular Papers
Protein Structural Class Prediction via k-Separated Bigrams Using Position Specific Scoring Matrix
Harsh SainiGaurav RaicarAlok SharmaSunil LalAbdollah DehzangiRajeshkannan AnanthanarayananJames LyonsNeela BiswasKuldip K. Paliwal
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JOURNAL OPEN ACCESS

2014 Volume 18 Issue 4 Pages 474-479

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Abstract

Protein structural class prediction (SCP) is as important task in identifying protein tertiary structure and protein functions. In this study, we propose a feature extraction technique to predict secondary structures. The technique utilizes bigram (of adjacent and k-separated amino acids) information derived from Position Specific Scoring Matrix (PSSM). The technique has shown promising results when evaluated on benchmarked Ding and Dubchak dataset.

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