Abstract
Adamantinoma in long bone is a rare malignant bone tumor in Japan. And more, few lung metastases were reported. A 33-year-old male was admitted for cystic tumors on left lung observed on a chest CT examination. He had left tibial amputation for adamantinoma 5 years ago. As the lung metastasis was suspected, he underwent open lung biopsy of left lower lobe. Histological finding showed metastatic tumors of adamantinoma. One year after operation, chest CT examination did not show any recurrence on lungs, although, in 10 months after the examination, he complained of bloody sputum. Chest CT examination demonstrated tumor mass on his left lower lobe. On bronchoscopy, a tumor was detected in B
10. The patient underwent left lower lobectomy. On pathological examination, the metastatic tumor demonstrated abundant mitoses and mib-1 positive cells. These features were more prominent in the second metastatie tumor than in the prior metastatic tumor. Therefore, the secondary metastatic tumor represented rapid growth. This finding suggests that patients require careful observation for several years after the resection of metastatic tumors of adamantinoma in lung.
