2006 Volume 20 Issue 2 Pages 205-208
We herein reported two cases of non-small cell lung cancer with negative fluorine- 18 fluorodeoxyglucose positron emission tomography (FDG-PET) scanning. FDG-PET is very sensitive to the detection of lung cancer which appeared as a solid nodule on chest computed tomography (CT), even though pure bronchioloalveolar carcinomas which show a ground glass opacity on chest CT often show negative FDG-PET scanning. In our cases, well-defined solid nodular shadows on chest CT with negative FDG-PET scanning were diagnosed as adenocarcinoma by open lung biopsy. Mucin or low density of malignant cells can be a cause of false-negative FDG-PET scanning.
