2007 Volume 21 Issue 5 Pages 655-658
Mesothelioma rarely metastasizes to the skin. Most previously reported cases of cutaneous imvolvement by mesothelioma have been due to local extension or contamination of surgical sites. We report a case with subcutaneous metastasis of malignant pleural mesothelioma. A 52-year-old woman presented with a small skin nodule of the right chest. She had undergone extrapleural pneumonectomy for malignant pleural mesoshelioma 7 years before. Resection of the skin nodule was performed, and the diagnosis of subcutaneous metastasis of mesothelioma was confirmed with positive immunohistochemical stains for anti-calretinin, HBME-1, anti-cytokeratin, and EMA and negative stains for CEA.