Abstract
Most synovial sarcomas affect deep soft tissues of the extremities. Primary pulmonary synovial sarcoma is extremely rare. We report a case of primary pulmonary synovial sarcoma. A 59-year-old woman was admitted to our hospital for the treatment of a tumor of the left lung, which showed rapid growth over a period of 4 months on CT images. We diagnosed the tumor as a primary lung cancer with a rare histological subtype before surgery based on a cytological specimen obtained by bronchoscopy, composed of atypical spindle cells. We performed a left lower lobectomy with lymph node dissection. The tumor showed the proliferation of spindle cells, and the final diagnosis was confirmed by immunohistologic findings and genetic analysis for the detection of SYT gene rearrangement using fluorescence in situ hybridization (FISH). The patient was alive as of 18 months after surgery without recurrence.
