Abstract
A 66-year-old woman, who had undergone computed-tomography as a follow-up for laryngeal cancer, had been pointed out as showing double tumor shadows in the right upper lobe and thickening of the pulmonary interstices. With a diagnosis of primary lung cancer complicated by interstitial pneumonia (IP), we performed a right upper lobectomy. The diagnoses were squamous cell carcinoma and adenocarcinoma, double primary cancer. After the first lung surgery, she received partial lung resection two times; the diagnoses were large cell neuroendocrine carcinoma and squamous cell carcinoma.IP is well-known as a risk factor for lung cancer, but it is very rare that someone has metachronous multiple occurrences of three pathological types of lung cancer. Because IP patients have the potential for multiple occurrences of lung cancer, they should undergo close follow-up to identify new lesion in an early stage.
