Abstract
We report a case of giant mediastinal goiter with acromegaly. A 59-year-old woman was admitted to our hospital because of an abnormal chest shadow. She had a history of acromegaly and resection of a pituitary tumor at age 34. Chest radiography and chest computed tomography on admission showed an upper left mediastinal tumor compressing the trachea, and serum growth hormone and insulin like growth factor I were elevated to 74.2 and 451 ng/ml, respectively. Cranial MRI showed recurrence of the pituitary tumor. Resection of the mediastinal tumor was performed with a neck hemi-collar incision and median sternotomy. The tumor had developed from the left lobe of the thyroid and its pathological diagnosis was follicular adenoma. Due to the high incidence of goiter in acromegalic patients, the thyroid function and morphology should be carefully monitored in patients with acromegaly.
