Abstract
Alpha-fetoprotein (AFP) -producing lung cancer is a histologically rare type of lung cancer. We report a case of postoperative multiple liver metastasis from alpha-fetoprotein-producing pulmonary adenocarcinoma. A 64-year-old man was suspected of having a lung carcinoma in his right upper lobe. The tumor was diagnosed as primary adenocarcinoma of the lung (cT1aN0M0, Stage 1A), and right upper lobectomy and node dissection were performed. Four months after the operation, the serum AFP measurement was elevated at 2,318 ng/ml, and a CT scan of the abdomen showed multiple liver tumors. The histological/immunohistochemical diagnosis from CT-guided liver biopsy was liver metastasis from AFP-producing pulmonary adenocarcinoma, and he has been undergoing chemotherapy.