A resected case of atypical bronchial carcinoid associated with multiple endocrine neoplasia type 1

Abstract

A 66-year-old female undergone parathyroidecomy for primary hyperparathyroidism at 54 years old. She was admitted to our hospital with an abnormal shadow in the right middle lung field detected on chest radiograph on an annual check-up. Chest computed tomography revealed atelectasis of the right middle lobe and a pancreatic tumor. The diagnosis of multiple endocrine neoplasm type 1 (MEN 1) was confirmed. Bronchoscopy revealed a polypoid tumor in the middle lobe bronchus, and a biopsy specimen yielded a histological diagnosis of typical carcinoid. Then, a right middle lobectomy with lymph node resection was performed, and postoperative examination of permanent sections revealed an atypical bronchial carcinoid. She is currently alive and no sign of recurrence has occurred to date at 3 years after the right middle lobectomy. It is rare for multiple endocrine neoplasia type 1 to be associated with atypical bronchial carcinoid, and so this case is reported with a review of the literature.