Abstract
A 75-year-old woman visited a local physician with a cough. Chest computed tomography showed a well-marginated, 25-mm nodule in the anterior mediastinum. She was referred to our hospital and recommended to undergo surgery because the nodule was suspected to be a thymoma; however, she refused resection, and wished to be followed-up. The nodule increased slightly over four years on chest computed tomography, and she subsequently decided to undergo surgery. Video-assisted thoracoscopic surgery was performed using carbon dioxide insufflation. The resected nodule was 35×25 mm, composed of multiple, discrete epithelial nodules separated by an abundant lymphocytic stroma. The resected specimen was diagnosed as micronodular thymoma with lymphoid stroma histologically.