Abstract
A 58-year-old woman with chronic kidney disease was referred to our hospital for a lung mass detected by chest radiograph and chest computed tomography (CT). Chest CT showed a smooth and well-defined nodule of 14 mm in the right upper lobe. The serum ProGRP level was very high, at 602 pg/mL. A preoperative pathological diagnosis was not obtained. The patient underwent a right upper lobectomy for the lung mass, and it revealed a typical pulmonary carcinoid tumor pathologically. Although the serum ProGRP level immediately decreased after surgery, it remained at 162 pg/mL. Serum ProGRP is a useful marker of small cell lung cancer, and is also known to show a high level in patients with renal dysfunction. This report describes an extremely rare case of a typical pulmonary carcinoid tumor with chronic kidney disease showing a markedly high level of serum ProGRP.
