The Journal of the Japanese Association for Chest Surgery
Online ISSN : 1881-4158
Print ISSN : 0919-0945
ISSN-L : 0919-0945
A case of pulmonary actinomycosis differentially diagnosed from pulmonary aspergillosis with massive hemoptysis
Mika HoshinoTakumi YamauraSatoshi MutoJun OhsugiMitsunori HiguchiHiroyuki Suzuki
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2015 Volume 29 Issue 2 Pages 187-192

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Abstract
A 50-year-old female with diabetes mellitus was admitted to our hospital because of recurrent hemoptysis. Chest computed tomography revealed a mass with air cavities and wall thickness. A blood test showed a systemic inflammatory reaction and the level of plasma aspergillus antigen was high. Initially, she was diagnosed with chronic necrotic pulmonary aspergillosis and administered an anti-fungal agent. Because the hemoptysis did not improve, she underwent right upper lobectomy as a curative surgery. Post-operative pathological findings showed fine hyphae in the removed materials but did not show the fungal body of Aspergillus. She was diagnosed with pulmonary actinomycosis. She has been well without any recurrent lesions for four years since surgery followed by one-year penicillin treatment. Pulmonary actinomycosis is often too difficult to definitively diagnose, because it is often necessary to distinguish it from lung cancer, pulmonary tuberculosis, and fungal infection. Cases of pulmonary actinomycosis with massive hemoptysis and pulmonary nodules may require early diagnosis and treatment.
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© 2015 The Japanese Association for Chest Surgery
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