Abstract
We report a case of thymic cancer successfully treated with S-1. A 50-year-old man underwent squamous cell thymic cancer resection with concomitant resection of the left brachiocephalic vein, left lung, and pericardium. Multiple left pleural disseminations were revealed during the operation. Postoperative radiotherapy of the mediastinum and left pleural cavity and combination chemotherapy of cisplatin and etoposide were performed. At approximately three years after surgery, the progression of the disseminated tumors occurred. Carboplatin/paclitaxel chemotherapy reduced the tumors, but the response duration was brief. Subsequent administration of S-1 markedly shrank the tumors, and the effectiveness has continued for three and a half years. This case suggests that S-1 may be effective for squamous cell thymic cancer.
