2018 Volume 32 Issue 2 Pages 244-249
Pleural well-differentiated papillary mesothelioma (PWDPM) is an extremely rare subtype of epitheloid mesothelioma. Herein, we report a case of PWDPM. A 51-year-old man who had a history of occupational asbestos exposure was referred to our hospital for the evaluation of pleural effusion. Thoracoscopic pleural biopsy was performed, and pathological examination established a diagnosis of PWDPM. Pleural effusion was observed again 2 years after the biopsy. The thoracoscopic findings revealed tumor enlargement, but there was no evidence of malignant cells. Severe pleural effusion was not observed after the pleurodesis. We considered that intensive follow-up and the selection of therapy were needed for multiple WDPM because there is a risk of recurrence or malignant transformation.