2018 Volume 32 Issue 4 Pages 500-503
A 66-year-old man was admitted to our hospital due to mediastinal lymphadenopathy. EBUS-TBNA was performed, and the diagnosis was carcinoma. In spite of various preoperative clinical examinations, the primary site was not determined. We preoperatively diagnosed him with mediastinal lymph node carcinoma of unknown primary site. Dissection of the right superior mediastinum was carried out through video-assisted thoracic surgery. The intraoperative histological diagnosis was poorly differentiated carcinoma of the lymph node. The final diagnosis was small cell carcinoma of the lymph node, and he received adjuvant concurrent chemoradiotherapy. He was alive and well without recurrence or abnormal appearance of the primary site 2 years after the operation. Small cell carcinoma in mediastinal lymph nodes without a recognizable primary site is extremely rare, but it was considered that aggressive multimodal therapy including surgical resection is effective.
