The Journal of the Japanese Association for Chest Surgery
Online ISSN : 1881-4158
Print ISSN : 0919-0945
ISSN-L : 0919-0945
Pulmonary mucosa-associated lymphoid tissue lymphoma: Report of four patients receiving lung resection followed by chemotherapy
Hayato NanamiRyo MiyoshiKyoko HijiyaToshiaki MorikiAkinori MaedaKoji Chihara
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2021 Volume 35 Issue 4 Pages 326-331

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Abstract

We report four patients (3 females and 1 male, mean age of 62 years) with pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma confirmed by lung resection, and followed by chemotherapy. They had various CT features such as a well-circumscribed mass, nodule, or consolidation mimicking lung cancer. Bronchoscopy was performed for three of the four, but failed to result in a definitive diagnosis in any case. Lung resection was performed in all patients for the purposes of diagnosis and treatment, and pathological examination led to a definitive diagnosis of pulmonary MALT lymphoma. Adjuvant chemotherapy was performed in two patients, while it was administered as treatment for newly appearing lesions in other organs during the long-term follow-up period. One of the four patients died of another cancer 25 years after surgery. Three patients survived for 11 years, 2 and a half years, and 1 year and 8 months after surgery, respectively. We believe that pulmonary resection combined with close follow-up and treatment by a hematologist is effective to treat patients with pulmonary MALT lymphoma.

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© 2021 The Japanese Association for Chest Surgery
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