The Journal of the Japanese Association for Chest Surgery
Online ISSN : 1881-4158
Print ISSN : 0919-0945
ISSN-L : 0919-0945
Two cases of thoracic inflammatory myofibroblastic tumor and one case of inflammatory pseudotumor with difficult pre- and intraoperative diagnoses
Yosuke KiriyamaTsuyoshi UenoHiroshi SuehisaHisayuki ShigematsuNorihiro TeramotoMotohiro Yamashita
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2021 Volume 35 Issue 5 Pages 565-571

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Abstract

An inflammatory pseudotumor (IPT) is an uncommon lesion composed of spindle cell (resembling myofibroblastic cells) proliferation and inflammatory cell infiltration with lymphocytes and plasma cells. An inflammatory myofibroblastic tumor (IMT), which had been included in IPT, is predominantly composed of myofibroblastic cells and has a malignant phenotype. Preoperative diagnosis is often difficult due to the lack of specific radiographic findings and an insufficient amount of tissue needed for diagnosis. We report two cases of IMT and one case of IPT. Case 1: A 30-year-old female had right hypochondrial pain. Computed tomography (CT) showed a 7.8 cm mass on the right diaphragm. A solitary fibrous tumor was suspected and resected. The postoperative pathological diagnosis was IMT. Case 2: A 58-year-old female. Post-surgical follow-up CT of breast cancer revealed a 1.4 cm nodule in the right lower lobe of the lung. It was suspected to be primary or metastatic lung cancer, and lower lobectomy was performed. The pathological diagnosis revealed IMT. Case 3: A 60-year-old female had an abnormal shadow pointed out in her health check-up. CT showed a 3.5 cm irregular mass in the right lower lobe of the lung. The preoperative diagnosis was IMT by CT-guided lung biopsy and lower lobectomy was performed. The pathological diagnosis of resected specimens was IPT. In all 3 cases, we could diagnose patients after resection.

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© 2021 The Japanese Association for Chest Surgery
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