2021 Volume 35 Issue 6 Pages 705-711
Micronodular thymoma with lymphoid stroma (MNTLS) is rare, accounting for 1.4% of the total cases of thymoma. We report two surgical cases of MNTLS. Case 1: The patient was a 60-year-old woman who had a 17-mm nodule in the anterior mediastinum that was revealed by chest computed tomography during a medical checkup. We performed video-assisted thoracoscopic thymectomy. Case 2: The patient was a 70-year-old woman who had an 18-mm nodule in the anterior mediastinum that was also revealed by chest computed tomography during a medical checkup. We performed video-assisted thoracoscopic thymectomy. Both resected tumors were well-defined and homogenously white in color. Histopathological findings of the tumors revealed separation by an abundant lymphoid stroma with a field of tumor cells. Immunohistochemical staining showed that the tumors were positive for pankeratin in the field of tumor cells. The histopathological diagnosis was MNTLS. The long-term outcomes after the resection of MNTLS were good in previous reports. Case 1 has survived without recurrence for four years, and Case 2 has survived without recurrence for one year and six months.
