Pulmonary mucosa-associated lymphoid tissue lymphoma that developed after resection of pulmonary large cell neuroendocrine carcinoma

Abstract

We report a rare case of resection of pulmonary MALT lymphoma that occurred after resection of large cell neuroendocrine cancer. The patient was a 70-year-old woman. She underwent right lower lobectomy for stage IA2 right pulmonary large cell neuroendocrine carcinoma. On the suspicion of stage IA second lung cancer because a ground-glass nodule appeared in the middle lobe of the right lung on chest CT 5 years after the operation, thoracoscopic right middle lobe resection was performed. Histopathologically, she was diagnosed with pulmonary MALT lymphoma. Now, at 8 months after the operation, there has been no recurrence and the patient is being followed up. MALT lymphoma is associated with chronic inflammation due to various factors, but there are limited reports of lung MALT lymphoma associated with lung cancer. Further case accumulation is needed to clarify the relationship between the two diseases and treatment policy.