A case of tumor composed of coincident lung adenocarcinoma and mantle cell lymphoma

Abstract

The patient was a 76-year-old man. Six months ago, upon noticing a slight fever and enlarged lymph nodes throughout his body, he visited his regular physician. Thoracoabdominal CT showed a 25-mm nodule in his right lung apex, and an inguinal lymph node biopsy was conducted for diagnosis. He was subsequently diagnosed with mantle cell lymphoma (MCL). Primary lung cancer could not be ruled out for the lung lesion based on its imaging characteristics, so the patient was referred to our department for diagnosis and treatment. Thoracoscopic wedge resection of the right lung was conducted to facilitate biopsy. He was subsequently diagnosed with a tumor composed of coincident adenocarcinoma and MCL. The inguinal lymph node biopsy yielded a diagnosis of MCL, which was considered to be more advanced than the adenocarcinoma. The patient's postoperative course was uneventful. For these reasons, treatment for MCL was promptly started with the involvement of the patient's regular physician. This treatment was effective. Although recurrence was observed after achieving complete remission, the disease stabilized upon restarting treatment. No recurrence of lung cancer has been observed in the 7-year span since his surgery.