Abstract
We performed surgical treatment for the plasmacytoma of the sternum associated with Takatsuki's disease (POEMS syndrome or Crow-Fukase syndorome).
A 48-year-old man was admitted to our hospital with complaints of abdominal distention and progressive edema and numbness of the lower extremities. On physical examination, hyperpigmentation, gynecomastia, generalized lymphadenopathy, hepatosplenomegaly, and an osteosclerotic lesion of the sternum were observed. Laboratory data revealed IgA-λ type M-component, elevated LH and FSH, low testosterone, low T3 and elevated TSH in the serum, and elevated urinary estrogens.
We resected the solitary myeloma of rht sternum in conjunction with steroid therapy. The sternal body with the sclerotic lesion was resected from the second through the fifth costal cartilages. The defect was repaired with Dexon mesh and Marlex mesh to prevent paradoxical respiration. No postoperative complications were observed. Histopathological diagnosis was IgA-λ type plasmacytoma.
The remarkable effect of removal of the plasmacytoma on the course of the disease was not immediately observed but the patient is in remission.
