Abstract
A 52-year-old male was admitted because of an abnormal lesion of right lung. The total W. B. C. count was 1600 with 19% neutrophils. At surgery, it was found that the thymoma invaded the SVC, innominate vein, pericardium, and right lung. The histology of the tumor showed mixed type thymoma. The patient's neutophile count recovered to a normal level 6 months after surgery. Since then this patient has been admitted to our clinic nine times because of recurrence of the thymoma. CDDP was repeatedly injected into the right bronchial artery and costal artery. Severe anemia developed 33 months following surgery. Bone marrow examination revealed pure red cell aplasia, which responded somewhat to blood transfusions and corticosteroids and chemotherapy. However, the patient died of respiratory failure 46 months after surgery.
With the best of our knowledge, only six cases with invasive thymoma after surgery complicated with pure red cell aplasia, have been reported in the Japanese literatures.
