Abstract
A case of giant schwannoma with a low blood coagulation factor XIII activity was reported.
A 58 year-old-female was admitted to our hospital complaining of exertional dyspnea. Her blood coagulation factor XIII activity was less than 40% of standard plasma level. Chest roentogenogram and CT-scan demonstrated a chest wall tumor with pleural effusion in the right hemithorax. Thoracotomy was performed through the 5th intercostal space. Coagulation factor XIII concentrates were administrated intravenously for intrathoracic bleeding associated with a low coagulation factor XIII activity. Resected tumor was 19.5×14.5×13 cm in size and 1760 g in weight, and was microscopically diagnosed as a schwannoma originating from the intercostal nerve. Her blood coagulation factor XIII acitivity gradually increased after the operation.