The Journal of the Japanese Association for Chest Surgery
Online ISSN : 1881-4158
Print ISSN : 0919-0945
ISSN-L : 0919-0945
A case of ACTH-producing thymic carcinoid with metastasis to the labia majora after resection
Katsuhiko ShimizuYoshinori YamashitaEiji MiyaharaTetsuya Toge
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2000 Volume 14 Issue 7 Pages 841-845


This article reports a case of ACTH-producing thymic carcinoid with metastasis to the large pudendal lip after resection. A 26-year-old woman was admitted to our hospital because of hypertrichosis and moon face. The endocrinological examination revealed high plasma ACTH and serum cortisol levels, and Cushing syndrome was present. On CT scan, an anterior mediastinal tumor was detected. The tumor was totally resected with lymph node dissection through median stenotomy. Histologically, the tumor consisted of atypical thymic carcinoid with ACTH-production. After resection, clinical symptoms disappeared and ACTH and cortisol levels were normalized. The first recurrence involved the labia majora 15 months after surgery. The tumor was resected, and diagnosed as metastatic atypical thymic carcinoid histologically. ACTH-producing thymic carcinoid is extremely rare and its characterization is unclear. To date, there have been 15 reports regarding this tumor in Japan, and a collective review of this tumor was made.

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